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Efficient identification of identical-by-descent status in pedigrees with many untyped individuals

Motivation: Inference of identical-by-descent (IBD) probabilities is the key in family-based linkage analysis. Using high-density single nucleotide polymorphism (SNP) markers, one can almost always infer haplotype configurations of each member in a family given all individuals being typed. Consequen...

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Detalhes bibliográficos
Main Authors: Li, Xin, Yin, Xiaolin, Li, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881406/
https://ncbi.nlm.nih.gov/pubmed/20529905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq222
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