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Efficient identification of identical-by-descent status in pedigrees with many untyped individuals
Motivation: Inference of identical-by-descent (IBD) probabilities is the key in family-based linkage analysis. Using high-density single nucleotide polymorphism (SNP) markers, one can almost always infer haplotype configurations of each member in a family given all individuals being typed. Consequen...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881406/ https://ncbi.nlm.nih.gov/pubmed/20529905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq222 |
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