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Haplotype Reconstruction in Large Pedigrees with Untyped Individuals through IBD Inference

Haplotypes, as they specify the linkage patterns between dispersed genetic variations, provide important information for understanding the genetics of human traits. However, haplotypes are not directly obtainable from current genotyping platforms, which pushes extensive investigations of computation...

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Hlavní autoři: Li, Xin, Li, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216110/
https://ncbi.nlm.nih.gov/pubmed/21923410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2011.0167
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