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Vavien: An Algorithm for Prioritizing Candidate Disease Genes Based on Topological Similarity of Proteins in Interaction Networks

Genome-wide linkage and association studies have demonstrated promise in identifying genetic factors that influence health and disease. An important challenge is to narrow down the set of candidate genes that are implicated by these analyses. Protein-protein interaction (PPI) networks are useful in...

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Autori principali: Erten, Sinan, Bebek, Gurkan, Koyutürk, Mehmet
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216100/
https://ncbi.nlm.nih.gov/pubmed/22035267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2011.0154
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