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Prioritization of candidate disease genes by topological similarity between disease and protein diffusion profiles
BACKGROUND: Identification of gene-phenotype relationships is a fundamental challenge in human health clinic. Based on the observation that genes causing the same or similar phenotypes tend to correlate with each other in the protein-protein interaction network, a lot of network-based approaches wer...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622672/ https://ncbi.nlm.nih.gov/pubmed/23734762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S5-S5 |
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