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Vavien: An Algorithm for Prioritizing Candidate Disease Genes Based on Topological Similarity of Proteins in Interaction Networks

Genome-wide linkage and association studies have demonstrated promise in identifying genetic factors that influence health and disease. An important challenge is to narrow down the set of candidate genes that are implicated by these analyses. Protein-protein interaction (PPI) networks are useful in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Erten, Sinan, Bebek, Gurkan, Koyutürk, Mehmet
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216100/
https://ncbi.nlm.nih.gov/pubmed/22035267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2011.0154
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