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A Novel Alignment Method and Multiple Filters for Exclusion of Unqualified Peptides To Enhance Label-Free Quantification Using Peptide Intensity in LC—MS/MS

[Image: see text] Though many software packages have been developed to perform label-free quantification of proteins in complex biological samples using peptide intensities generated by LC–MS/MS, two critical issues are generally ignored in this field: (i) peptides have multiple elution patterns acr...

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Detalhes bibliográficos
Main Authors: Lai, Xianyin, Wang, Lianshui, Tang, Haixu, Witzmann, Frank A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216047/
https://ncbi.nlm.nih.gov/pubmed/21888428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr2005633
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