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GENES AS INSTRUMENTS FOR STUDYING RISK BEHAVIOR EFFECTS: AN APPLICATION TO MATERNAL SMOKING AND OROFACIAL CLEFTS

This study uses instrumental variable (IV) models with genetic instruments to assess the effects of maternal smoking on the child’s risk of orofacial clefts (OFC), a common birth defect. The study uses genotypic variants in neurotransmitter and detoxification genes relateded to smoking as instrument...

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Bibliografiske detaljer
Main Authors: Wehby, George, Jugessur, Astanand, Murray, Jeffrey C., Moreno, Lina, Wilcox, Allen, Lie, Rolv T.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216039/
https://ncbi.nlm.nih.gov/pubmed/22102793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10742-011-0071-9
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