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GENES AS INSTRUMENTS FOR STUDYING RISK BEHAVIOR EFFECTS: AN APPLICATION TO MATERNAL SMOKING AND OROFACIAL CLEFTS

This study uses instrumental variable (IV) models with genetic instruments to assess the effects of maternal smoking on the child’s risk of orofacial clefts (OFC), a common birth defect. The study uses genotypic variants in neurotransmitter and detoxification genes relateded to smoking as instrument...

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Detalhes bibliográficos
Main Authors: Wehby, George, Jugessur, Astanand, Murray, Jeffrey C., Moreno, Lina, Wilcox, Allen, Lie, Rolv T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216039/
https://ncbi.nlm.nih.gov/pubmed/22102793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10742-011-0071-9
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