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Application of a novel hybrid study design to explore gene-environment interactions in orofacial clefts
Orofacial clefts are common birth defects with strong evidence for both genetic and environmental causal factors. Candidate-gene studies combined with exposures known to influence the outcome provide a highly targeted approach to detecting GxE interactions. We developed a new statistical approach th...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3334353/ https://ncbi.nlm.nih.gov/pubmed/22497478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2012.00707.x |
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