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Application of a novel hybrid study design to explore gene-environment interactions in orofacial clefts

Orofacial clefts are common birth defects with strong evidence for both genetic and environmental causal factors. Candidate-gene studies combined with exposures known to influence the outcome provide a highly targeted approach to detecting GxE interactions. We developed a new statistical approach th...

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Autori principali: Skare, Øivind, Jugessur, Astanand, Lie, Rolv Terje, Wilcox, Allen James, Murray, Jeffrey Clark, Lunde, Astrid, Nguyen, Truc Trung, Gjessing, Håkon Kristian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334353/
https://ncbi.nlm.nih.gov/pubmed/22497478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2012.00707.x
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