Sir2 deletion prevents lifespan extension in 32 long-lived mutants

Activation of Sir2-orthologs is proposed to increase lifespan downstream of dietary restriction (DR). Here we describe an examination of the effect of 32 different lifespan-extending mutations and four methods of dietary restriction on replicative lifespan (RLS) in the short-lived sir2Δ yeast strain...

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Detaylı Bibliyografya
Asıl Yazarlar: Delaney, Joe R., Sutphin, George L., Dulken, Ben, Sim, Sylvia, Kim, Jin R., Robison, Brett, Schleit, Jennifer, Murakami, Christopher J., Carr, Daniel, An, Elroy H., Choi, Eunice, Chou, Annie, Fletcher, Marissa, Jelic, Monika, Liu, Bin, Lockshon, Daniel, Moller, Richard M., Pak, Diana N., Peng, Qi, Peng, Zhao J., Pham, Kim M., Sage, Michael, Solanky, Amrita, Steffen, Kristan K., Tsuchiya, Mitsuhiro, Tsuchiyama, Scott, Johnson, Simon, Raabe, Chris, Suh, Yousin, Zhou, Zhongjun, Liu, Xinguang, Kennedy, Brian K., Kaeberlein, Matt
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215821/
https://ncbi.nlm.nih.gov/pubmed/21902802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00742.x
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