A comprehensive analysis of replicative lifespan in 4,698 single-gene deletion strains uncovers conserved mechanisms of aging

Many genes that affect replicative lifespan (RLS) in the budding yeast Saccharomyces cerevisiae also affect aging in other organisms such as C. elegans and M. musculus. We performed a systematic analysis of yeast RLS in a set of 4,698 viable single-gene deletion strains. Multiple functional gene clu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: McCormick, Mark A., Delaney, Joe R., Tsuchiya, Mitsuhiro, Tsuchiyama, Scott, Shemorry, Anna, Sim, Sylvia, Chou, Annie Chia-Zong, Ahmed, Umema, Carr, Daniel, Murakami, Christopher J., Schleit, Jennifer, Sutphin, George L., Wasko, Brian M., Bennett, Christopher F., Wang, Adrienne M., Olsen, Brady, Beyer, Richard P., Bammler, Theodor K., Prunkard, Donna, Johnson, Simon C., Pennypacker, Juniper K., An, Elroy, Anies, Arieanna, Castanza, Anthony S., Choi, Eunice, Dang, Nick, Enerio, Shiena, Fletcher, Marissa, Fox, Lindsay, Goswami, Sarani, Higgins, Sean A., Holmberg, Molly A., Hu, Di, Hui, Jessica, Jelic, Monika, Jeong, Ki-Soo, Johnston, Elijah, Kerr, Emily O., Kim, Jin, Kim, Diana, Kirkland, Katie, Klum, Shannon, Kotireddy, Soumya, Liao, Eric, Lim, Michael, Lin, Michael S., Lo, Winston C., Lockshon, Dan, Miller, Hillary A., Moller, Richard M., Muller, Brian, Oakes, Jonathan, Pak, Diana N., Peng, Zhao Jun, Pham, Kim M., Pollard, Tom G., Pradeep, Prarthana, Pruett, Dillon, Rai, Dilreet, Robison, Brett, Rodriguez, Ariana A., Ros, Bopharoth, Sage, Michael, Singh, Manpreet K., Smith, Erica D., Snead, Katie, Solanky, Amrita, Spector, Benjamin L., Steffen, Kristan K., Tchao, Bie Nga, Ting, Marc K., Wende, Helen Vander, Wang, Dennis, Welton, K. Linnea, Westman, Eric A., Brem, Rachel B., Liu, Xin-guang, Suh, Yousin, Zhou, Zhongjun, Kaeberlein, Matt, Kennedy, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862740/
https://ncbi.nlm.nih.gov/pubmed/26456335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.09.008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados