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Domain architecture conservation in orthologs

BACKGROUND: As orthologous proteins are expected to retain function more often than other homologs, they are often used for functional annotation transfer between species. However, ortholog identification methods do not take into account changes in domain architecture, which are likely to modify a p...

詳細記述

保存先:
書誌詳細
主要な著者: Forslund, Kristoffer, Pekkari, Isabella, Sonnhammer, Erik LL
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215765/
https://ncbi.nlm.nih.gov/pubmed/21819573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-326
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