Association of MDR1 Gene SNPs and Haplotypes with the Tacrolimus Dose Requirements in Han Chinese Liver Transplant Recipients

BACKGROUND: This work seeks to evaluate the association between the C/D ratios (plasma concentration of tacrolimus divided by daily dose of tacrolimus per body weight) of tacrolimus and the haplotypes of MDR1 gene combined by C1236T (rs1128503), G2677A/T (rs2032582) and C3435T (rs1045642), and to fu...

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Detalhes bibliográficos
Main Authors: Yu, Xiaobo, Xie, Haiyang, Wei, Bajin, Zhang, Min, Wang, Weilin, Wu, Jian, Yan, Sheng, Zheng, Shusen, Zhou, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215699/
https://ncbi.nlm.nih.gov/pubmed/22110582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025933
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