Multiplex PCR Amplimer Conformation Analysis for Rapid Detection of gyrA Mutations in Fluoroquinolone-Resistant Mycobacterium tuberculosis Clinical Isolates

A new strategy known as multiplex PCR amplimer conformation was developed for detection of mutation in the gyrA gene of 138 clinical isolates of Mycobacterium tuberculosis. The method generated a single-stranded and heteroduplex DNA banding pattern of multiplex PCR amplimers of the region of interes...

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Autori principali: Cheng, Augustine F. B., Yew, Wing W., Chan, Edward W. C., Chin, Miu L., Hui, Mamie M. M., Chan, Raphael C. Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC321542/
https://ncbi.nlm.nih.gov/pubmed/14742214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.2.596-601.2004
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