Molecular Characterization of Fluoroquinolone Resistance in Mycobacterium tuberculosis: Functional Analysis of gyrA Mutation at Position 74

A PCR-sequencing assay was evaluated for direct detection of mutations in the quinolone resistance-determining region (QRDR) of gyrase A (gyrA) gene in fluoroquinolone-resistant Mycobacterium tuberculosis in respiratory specimens. As determined by gyrA QRDR analysis, complete concordance of genotypi...

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Detalhes bibliográficos
Main Authors: Lau, Ricky W. T., Ho, Pak-Leung, Kao, Richard Y. T., Yew, Wing-Wai, Lau, Terrence C. K., Cheng, Vincent C. C., Yuen, Kwok-Yung, Tsui, Stephen K. W., Chen, Xinchun, Yam, Wing-Cheong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028802/
https://ncbi.nlm.nih.gov/pubmed/20956608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00920-10
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