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Characterizing genetic interactions in human disease association studies using statistical epistasis networks
BACKGROUND: Epistasis is recognized ubiquitous in the genetic architecture of complex traits such as disease susceptibility. Experimental studies in model organisms have revealed extensive evidence of biological interactions among genes. Meanwhile, statistical and computational studies in human popu...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3215301/ https://ncbi.nlm.nih.gov/pubmed/21910885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-364 |
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