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Characterizing gene-gene interactions in a statistical epistasis network of twelve candidate genes for obesity

BACKGROUND: Recent findings have reemphasized the importance of epistasis, or gene-gene interactions, as a contributing factor to the unexplained heritability of obesity. Network-based methods such as statistical epistasis networks (SEN), present an intuitive framework to address the computational c...

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Vydáno v:BioData Min
Hlavní autoři: De, Rishika, Hu, Ting, Moore, Jason H., Gilbert-Diamond, Diane
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693412/
https://ncbi.nlm.nih.gov/pubmed/26715945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13040-015-0077-x
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