Characterizing genetic interactions in human disease association studies using statistical epistasis networks

BACKGROUND: Epistasis is recognized ubiquitous in the genetic architecture of complex traits such as disease susceptibility. Experimental studies in model organisms have revealed extensive evidence of biological interactions among genes. Meanwhile, statistical and computational studies in human popu...

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Autors principals: Hu, Ting, Sinnott-Armstrong, Nicholas A, Kiralis, Jeff W, Andrew, Angeline S, Karagas, Margaret R, Moore, Jason H
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215301/
https://ncbi.nlm.nih.gov/pubmed/21910885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-364
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