Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration

We introduce a human retinal pigmented epithelial (RPE) cell-culture model that mimics several key aspects of early stage age-related macular degeneration (AMD). These include accumulation of sub-RPE deposits that contain molecular constituents of human drusen, and activation of complement leading t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Johnson, Lincoln V., Forest, David L., Banna, Christopher D., Radeke, Carolyn M., Maloney, Michelle A., Hu, Jane, Spencer, Christine N., Walker, Aimee M., Tsie, Marlene S., Bok, Dean, Radeke, Monte J., Anderson, Don H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215058/
https://ncbi.nlm.nih.gov/pubmed/21969589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109703108
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados