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Impaired Brain Creatine Kinase Activity in Huntington's Disease

BACKGROUND: Huntington's disease (HD) is associated with impaired energy metabolism in the brain. Creatine kinase (CK) catalyzes ATP-dependent phosphorylation of creatine (Cr) into phosphocreatine (PCr), thereby serving as readily available high-capacity spatial and temporal ATP buffering. Obje...

詳細記述

保存先:
書誌詳細
主要な著者: Zhang, S.F., Hennessey, T., Yang, L., Starkova, N.N., Beal, M.F., Starkov, A.A.
フォーマット: Artigo
言語:Inglês
出版事項: S. Karger AG 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214941/
https://ncbi.nlm.nih.gov/pubmed/21124007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000321681
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