Dysregulated brain creatine kinase is associated with hearing impairment in mouse models of Huntington disease

Huntington disease (HD) is a degenerative disorder caused by expanded CAG repeats in exon 1 of the huntingtin gene (HTT). Patients with late-stage HD are known to have abnormal auditory processing, but the peripheral auditory functions of HD patients have yet to be thoroughly assessed. In this study...

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Main Authors: Lin, Yow-Sien, Chen, Chiung-Mei, Soong, Bing-wen, Wu, Yih-Ru, Chen, Hui-Mei, Yeh, Wen-Ying, Wu, Dai-Rong, Lin, Yi-Jun, Poon, Paul Wai-Fung, Cheng, Mei-Ling, Wang, Chih-Hung, Chern, Yijuang
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2011
Ábhair:
Brief Report
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069762/
https://ncbi.nlm.nih.gov/pubmed/21403395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43220
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