Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington’s disease

Huntington’s disease (HD) is a neurodegenerative disorder that manifests with movement dysfunction. The expression of mutant Huntingtin (mHTT) disrupts the functions of brain cells. Galectin-3 (Gal3) is a lectin that has not been extensively explored in brain diseases. Herein, we showed that the pla...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Siew, Jian Jing, Chen, Hui-Mei, Chen, Huan-Yuan, Chen, Hung-Lin, Chen, Chiung-Mei, Soong, Bing-Wen, Wu, Yih-Ru, Chang, Ching-Pang, Chan, Yi-Chen, Lin, Chun-Hung, Liu, Fu-Tong, Chern, Yijuang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677843/
https://ncbi.nlm.nih.gov/pubmed/31375685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11441-0
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