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Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington’s disease
Huntington’s disease (HD) is a neurodegenerative disorder that manifests with movement dysfunction. The expression of mutant Huntingtin (mHTT) disrupts the functions of brain cells. Galectin-3 (Gal3) is a lectin that has not been extensively explored in brain diseases. Herein, we showed that the pla...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6677843/ https://ncbi.nlm.nih.gov/pubmed/31375685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11441-0 |
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