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Impaired Brain Creatine Kinase Activity in Huntington's Disease
BACKGROUND: Huntington's disease (HD) is associated with impaired energy metabolism in the brain. Creatine kinase (CK) catalyzes ATP-dependent phosphorylation of creatine (Cr) into phosphocreatine (PCr), thereby serving as readily available high-capacity spatial and temporal ATP buffering. Obje...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3214941/ https://ncbi.nlm.nih.gov/pubmed/21124007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000321681 |
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