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ΔNp63α regulates keratinocyte proliferation by controlling PTEN expression and localization
ΔNp63α, implicated as an oncogene, is upregulated by activated Akt, part of a well-known cell survival pathway. Inhibition of Akt activation by phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and the presence of putative p63-binding sites in the pten promoter led us to investigate whe...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3214913/ https://ncbi.nlm.nih.gov/pubmed/21637289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.73 |
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