1α, 25-Dihydroxyvitamin D(3) and the vitamin D receptor regulates ΔNp63α levels and keratinocyte proliferation

1α, 25-dihydroxyvitamin D(3) (VD(3)), a secosteriod that has been explored as an anti-cancer agent, was also shown to promote cell survival. Its receptor, the Vitamin D Receptor (VDR), is a direct target of the proto-oncogene ΔNp63α, which is overexpressed in non-melanoma skin cancers. The interconn...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Hill, N T, Zhang, J, Leonard, M K, Lee, M, Shamma, H N, Kadakia, M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669830/
https://ncbi.nlm.nih.gov/pubmed/26068789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.148
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