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All-Atom and Coarse-Grained Molecular Dynamics Simulations of a Membrane Protein Stabilizing Polymer

Amphipathic polymers called amphipols (APols) have been developed as an alternative to detergents for stabilizing membrane proteins (MPs) in aqueous solutions. APols provide MPs with a particularly mild environment and, as a rule, keep them in a native and functional state for longer periods than de...

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Detalhes bibliográficos
Main Authors: Perlmutter, Jason D., Drasler, William J., Xie, Wangshen, Gao, Jiali, Popot, Jean-Luc, Sachs, Jonathan N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214636/
https://ncbi.nlm.nih.gov/pubmed/21806035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la202103v
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