Roles of p53 and p27 (Kip1) in the regulation of neurogenesis in the murine adult subventricular zone

The tumor suppressor protein p53 (Trp53) and the cell cycle inhibitor p27 (Kip1) (Cdknb1) have both been implicated in regulating proliferation of adult subventricular zone (aSVZ) cells. We previously reported that genetic ablation of Trp53 (Trp53 (−/−)) or Cdknb1 (p27 (Kip1−/−)) increased prolifera...

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Detalhes bibliográficos
Main Authors: Gil-Perotin, Sara, Haines, Jeffery D., Kaur, Jasbir, Marin-Husstege, Mireya, Spinetta, Michael J., Kim, Kwi-Hye, Duran-Moreno, Maria, Schallert, Timothy, Zindy, Frederique, Roussel, Martine F., Garcia-Verdugo, Jose M., Casaccia, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214596/
https://ncbi.nlm.nih.gov/pubmed/21899604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2011.07836.x
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