Lack of the Cell-Cycle Inhibitor p27Kip1 Results in Selective Increase of Transit-Amplifying Cells for Adult Neurogenesis

The subventricular zone (SVZ) is the largest germinal layer in the adult mammalian brain and comprises stem cells, transit-amplifying progenitors, and committed neuroblasts. Although the SVZ contains the highest concentration of dividing cells in the adult brain, the intracellular mechanisms control...

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Publicado en:J Neurosci
Autores principales: Doetsch, Fiona, Verdugo, José Manuel-Garcia, Caille, Isabelle, Alvarez-Buylla, Arturo, Chao, Moses V., Casaccia-Bonnefil, Patrizia
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758265/
https://ncbi.nlm.nih.gov/pubmed/11896165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-06-02255.2002
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