Phosphorylation of Serine 18 Regulates Distinct p53 Functions in Mice

The p53 protein acts a tumor suppressor by inducing cell cycle arrest and apoptosis in response to DNA damage or oncogene activation. Recently, it has been proposed that phosphorylation of serine 15 in human p53 by ATM (mutated in ataxia telangiectasia) kinase induces p53 activity by interfering wit...

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Bibliographic Details
Main Authors: Sluss, Hayla K., Armata, Heather, Gallant, Judy, Jones, Stephen N.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC321447/
https://ncbi.nlm.nih.gov/pubmed/14729946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.3.976-984.2004
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