Nicotinamide Clearance by Pnc1 Directly Regulates Sir2-Mediated Silencing and Longevity
The Saccharomyces cerevisiae Sir2 protein is an NAD(+)-dependent histone deacetylase (HDAC) that functions in transcriptional silencing and longevity. The NAD(+) salvage pathway protein, Npt1, regulates Sir2-mediated processes by maintaining a sufficiently high intracellular NAD(+) concentration. Ho...
I tiakina i:
| I whakaputaina i: | Mol Cell Biol |
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| Ngā kaituhi matua: | , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Taylor & Francis
2004
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| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321434/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14729974/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.3.1301-1312.2004 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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