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The Corepressor mSin3A Regulates Phosphorylation-Induced Activation, Intranuclear Location, and Stability of AML1

The AML1 (RUNX1) gene, one of the most frequent targets of translocations associated with human leukemias, encodes a DNA-binding protein that plays pivotal roles in myeloid differentiation through transcriptional regulation of various genes. Previously, we reported that AML1 is phosphorylated on two...

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Published in:Mol Cell Biol
Main Authors: Imai, Yoichi, Kurokawa, Mineo, Yamaguchi, Yuko, Izutsu, Koji, Nitta, Eriko, Mitani, Kinuko, Satake, Masanobu, Noda, Tetsuo, Ito, Yoshiaki, Hirai, Hisamaru
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2004
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321417/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14729951/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.3.1033-1043.2004
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