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The PHD Finger of Human UHRF1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers

The human UHRF1 protein (ubiquitin-like containing PHD and RING finger domains 1) has emerged as a potential cancer target due to its implication in cell cycle regulation, maintenance of DNA methylation after replication and heterochromatin formation. UHRF1 functions as an adaptor protein that binds...

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Detalhes bibliográficos
Main Authors: Lallous, Nada, Legrand, Pierre, McEwen, Alastair G., Ramón-Maiques, Santiago, Samama, Jean-Pierre, Birck, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214078/
https://ncbi.nlm.nih.gov/pubmed/22096602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027599
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