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Expression, purification, crystallization and preliminary crystallographic study of the SRA domain of the human UHRF1 protein

Human UHRF1 belongs to the unique mammalian family of proteins which contain a SET- and RING finger-associated (SRA) domain. This 180-residue domain has been reported to play key roles in the functions of the protein. It allows UHRF1 to bind methylated DNA, histone deacetylase 1 and DNA methyltransf...

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Detalhes bibliográficos
Main Authors: Delagoutte, Bénédicte, Lallous, Nada, Birck, Catherine, Oudet, Pierre, Samama, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564892/
https://ncbi.nlm.nih.gov/pubmed/18931436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108027462
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