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A Role for the Ubiquitin Ligase Nedd4 in Membrane Sorting of LAPTM4 Proteins
BACKGROUND: The Lysosome associated protein transmembrane (LAPTM) family is comprised of three members: LAPTM5, LAPTM4a and LAPTM4b, with the latter previously shown to be overexpressed in numerous cancers. While we had demonstrated earlier the requirement of the E3 ubiquitin ligase Nedd4 for LAPTM5...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3214061/ https://ncbi.nlm.nih.gov/pubmed/22096579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027478 |
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