Simian Immunodeficiency Virus Promoter Exchange Results in a Highly Attenuated Strain That Protects against Uncloned Challenge Virus

Among the many simian immunodeficiency virus (SIV) immunogens, only live attenuated viral vaccines have afforded strong protection to a natural pathogenic isolate. Since the promoter is crucial to the tempo of viral replication in general, it was reasoned that promoter exchange might confer a novel...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Blancou, Philippe, Chenciner, Nicole, Fang, Raphaël Ho Tsong, Monceaux, Valérie, Cumont, Marie-Christine, Guétard, Denise, Hurtrel, Bruno, Wain-Hobson, Simon
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2004
Schlagworte:	Vaccines and Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14722263/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.3.1080-1092.2004
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