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Cell-Dependent Role for the Poliovirus 3′ Noncoding Region in Positive-Strand RNA Synthesis

We previously reported the isolation of a mutant poliovirus lacking the entire genomic RNA 3′ noncoding region. Infection of HeLa cell monolayers with this deletion mutant revealed only a minor defect in the levels of viral RNA replication. To further analyze the consequences of the genomic 3′ nonco...

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Autors principals: Brown, David M., Kauder, Steven E., Cornell, Christopher T., Jang, Gwendolyn M., Racaniello, Vincent R., Semler, Bert L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC321373/
https://ncbi.nlm.nih.gov/pubmed/14722289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.3.1344-1351.2004
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