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Translating Ribosomes Inhibit Poliovirus Negative-Strand RNA Synthesis

Poliovirus has a single-stranded RNA genome of positive polarity that serves two essential functions at the start of the viral replication cycle in infected cells. First, it is translated to synthesize viral proteins and, second, it is copied by the viral polymerase to synthesize negative-strand RNA...

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Detalhes bibliográficos
Main Authors: Barton, David J., Morasco, B. Joan, Flanegan, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113062/
https://ncbi.nlm.nih.gov/pubmed/10559325
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