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The Melatonin MT1 Receptor Axis Modulates Mutant Huntingtin-Mediated Toxicity
Melatonin mediates neuroprotection in several experimental models of neurodegeneration. It is not yet known, however, whether melatonin provides neuroprotection in genetic models of Huntington's disease (HD). We report that melatonin delays disease onset and mortality in a transgenic mouse mode...
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| 主要な著者: | , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3213696/ https://ncbi.nlm.nih.gov/pubmed/21994366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3059-11.2011 |
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