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Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications

For more than 60 years, the chemical induction of tumors in mouse skin has been used to study mechanisms of epithelial carcinogenesis and evaluate modifying factors. In the traditional two-stage skin carcinogenesis model, initiation is accomplished by the application of a subcarcinogenic dose of a c...

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Detalhes bibliográficos
Main Authors: Abel, Erika L., Angel, Joe M, Kiguchi, Kaoru, DiGiovanni, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213400/
https://ncbi.nlm.nih.gov/pubmed/19713956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2009.120
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