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siPRED: Predicting siRNA Efficacy Using Various Characteristic Methods

Small interfering RNA (siRNA) has been used widely to induce gene silencing in cells. To predict the efficacy of an siRNA with respect to inhibition of its target mRNA, we developed a two layer system, siPRED, which is based on various characteristic methods in the first layer and fusion mechanisms...

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Hlavní autoři: Pan, Wei-Jie, Chen, Chi-Wei, Chu, Yen-Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213166/
https://ncbi.nlm.nih.gov/pubmed/22102913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027602
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