Resveratrol inhibits Cdk5 activity through regulation of p35 expression

BACKGROUND: We have previously reported that cyclin-dependent kinase 5 (Cdk5) participates in the regulation of nociceptive signaling. Through activation of the ERK1/2 pathway, Tumor Necrosis Factor-α (TNF-α) induces expression of Egr-1. This results in the sustained and robust expression of p35, a...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Utreras, Elias, Terse, Anita, Keller, Jason, Iadarola, Michael J, Kulkarni, Ashok B
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212955/
https://ncbi.nlm.nih.gov/pubmed/21736731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-49
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky