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Crystallization and preliminary X-ray diffraction analysis of the human XRCC4–XLF complex

XRCC4 and XLF are key proteins in the repair of DNA double-strand breaks through nonhomologous end-joining. Together, they form a complex that stimulates the ligation of double-strand breaks. Owing to the suggested filamentous nature of this complex, structural studies via X-ray crystallography have...

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Detalhes bibliográficos
Main Authors: Andres, Sara N., Junop, Murray S.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212460/
https://ncbi.nlm.nih.gov/pubmed/22102241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111033549
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