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Crystallization and preliminary X-ray diffraction analysis of the human XRCC4–XLF complex
XRCC4 and XLF are key proteins in the repair of DNA double-strand breaks through nonhomologous end-joining. Together, they form a complex that stimulates the ligation of double-strand breaks. Owing to the suggested filamentous nature of this complex, structural studies via X-ray crystallography have...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
International Union of Crystallography
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3212460/ https://ncbi.nlm.nih.gov/pubmed/22102241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111033549 |
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