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Role of CYP2E1 in Ethanol-Induced Oxidant Stress, Fatty Liver and Hepatotoxicity

BACKGROUND/AIMS: Several pathways contribute to mechanisms by which ethanol induces oxidant stress. While some studies support a role for cytochrome P450 2E1 (CYP2E1), others do not. There is a need to develop oral models of significant ethanol-induced liver injury and to evaluate the possible role...

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Detalhes bibliográficos
Autor principal: Cederbaum, Arthur I.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211519/
https://ncbi.nlm.nih.gov/pubmed/21525766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000324289
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