Nanomechanical properties of α-synuclein amyloid fibrils: a comparative study by nanoindentation, harmonic force microscopy, and Peakforce QNM

We report on the use of three different atomic force spectroscopy modalities to determine the nanomechanical properties of amyloid fibrils of the human α-synuclein protein. α-Synuclein forms fibrillar nanostructures of approximately 10 nm diameter and lengths ranging from 100 nm to several microns,...

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Bibliographic Details
Main Authors: Sweers, Kim, van der Werf, Kees, Bennink, Martin, Subramaniam, Vinod
Format: Artigo
Language:Inglês
Published: Springer 2011
Subjects:
Nano Express
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211334/
https://ncbi.nlm.nih.gov/pubmed/21711775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1556-276X-6-270
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