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Enantioselective α-Arylation of Carbonyls via Cu(I)-Bisoxazoline Catalysis

The enantioselective α-arylation of both lactones and acyl oxazolidones has been accomplished using a combination of diaryliodonium salts and copper catalysis. These mild catalytic conditions provide a new strategy for the enantioselective construction and retention of enolizable α-carbonyl benzylic...

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Main Authors: Harvey, James S., Simonovich, Scott P., Jamison, Christopher R., MacMillan, David W. C.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211083/
https://ncbi.nlm.nih.gov/pubmed/21848265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja206050b
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