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The Enantioselective α-Arylation of Aldehydes via Organo-SOMO Catalysis. An Ortho-Selective Arylation Reaction Based on an Open-Shell Pathway

[Image: see text] The intramolecular α-arylation of aldehydes has been accomplished using singly occupied molecular orbital (SOMO) catalysis. Selective oxidation of chiral enamines (formed by the condensation of an aldehyde and a secondary amine catalyst) leads to the formation of a 3π-electron radi...

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Autors principals: Conrad, Jay C., Kong, Jongrock, Laforteza, Brian N., MacMillan, David W. C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758563/
https://ncbi.nlm.nih.gov/pubmed/19639997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9026902
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