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A COMMON HAPLOTYPE OF THE TUMOUR NECROSIS FACTOR RECEPTOR 2 GENE MODULATES ENDOTOXIN TOLERANCE
Endotoxin tolerance is characterized by the suppression of further TNF release upon recurrent exposure to LPS. This phenomenon is proposed to act as a homeostatic mechanism preventing uncontrolled cytokine release such as that observed in bacterial sepsis. The regulatory mechanisms and inter-individ...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3211060/ https://ncbi.nlm.nih.gov/pubmed/21282507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001791 |
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